A Clinicopathological study of uterine cervical lesions in a Tertiary Care Centre

Sujata Kumbhar (1) , Sujata Kanetkar (2) , Avinash Mane (3) , Akanksha Gore (4)
(1) Department of Pathology, Krishna Institute of Medical Sciences ‘Deemed To Be’ University, Karad, Maharashtra, India, India ,
(2) Department of Pathology, Krishna Institute of Medical Sciences ‘Deemed To Be’ University, Karad, Maharashtra, India, India ,
(3) Department of Pathology, Krishna Institute of Medical Sciences ‘Deemed To Be’ University, Karad, Maharashtra, India, India ,
(4) Department of Pathology, Krishna Institute of Medical Sciences ‘Deemed To Be’ University, Karad, Maharashtra, India, India

Abstract

Pap test is a simple yet effective screening method to detect cervical cancer in its early stage, and thus it helps to reduce morbidity and mortality from cancer. A total of 430 cases were studied after taking ethical clearance. The cytological diagnoses were made by Cytopathologist using Bethesda 2014 system for categorization of cervical smears. Cytological results were correlated with clinical features and histopathological results wherever biopsy was available. The total of the 430 cases studied 24 (5.58%) were inadequate to report, excluding these, of the total 406 cases 260 (64.04%) cases were symptomatic, and 146 (35.96%) were asymptomatic. Cytologic diagnoses were NILM –normal- 140 (55.23%)with a mean age of 38.48 years, NILM- inflammatory 128 (47.76%) with a mean age of 35.96 years, ASC-US 36 (8.86%) with a mean age of 36.69 years, ASC-H 18 (4.43%) with a mean age of 45 years, LSIL 42 (10.34%) with a mean age of 41.90, HSIL 22 (5.42%) with a mean age of 51.22 years, and invasive cancer 20 (4.92%) with a mean age of 61.8 years. Sensitivity, specificity, and positive predictive value, negative predictive value and accuracy of Pap test were 89.79%, 95.34%, and 95.65%, 89.13% and 83.33% respectively. Pap smear test is a simple, rapid, economical, still practical screening test to detect cervical intraepithelial lesions and cancer.

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Authors

Sujata Kumbhar
drsujatakumbhar@yahoo.in (Primary Contact)
Sujata Kanetkar
Avinash Mane
Akanksha Gore
Sujata Kumbhar, Sujata Kanetkar, Avinash Mane, & Akanksha Gore. (2020). A Clinicopathological study of uterine cervical lesions in a Tertiary Care Centre. International Journal of Research in Pharmaceutical Sciences, 11(4), 5860–5866. Retrieved from https://ijrps.com/home/article/view/1245

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