Antibacterial activity of Methanol and n-Hexane extracts of fruit casings of Quercus rubra against multi-drug resistance pathogenic bacteria isolated from patients with burn infection

Dhafer Rahman Abed Al-janabi (1) , Enas Abd al-Raouf Ammar Semysim (2)
(1) Department of Biology, University of Kufa, Faculty of Science, Iraq, Iraq ,
(2) Department of Biology, University of Kufa, Faculty of Science, Iraq, Iraq

Abstract

This study was designed to investigate the ability of methanol and n-hexane extracts of fruit casings of Quercus rubra against  pathogenic bacteria isolated from patients with burn infection. Three concentrations of methanol and n-Hexane extracts of Quercus  rubra were done (100, 200 and 400) mg/ml. Thirty eight samples were collected from Medical Burn Center in Najaf Governorate. Males  and females in different age groups. The results indicated that there were 42% pseudomonasaeroginosa, 22% Staphylococcusaureus,  18% Klebsiellapneumonia, 8% E. coli, 6% Staphylococcusepedermsis and 4% proteusmiribilis. Seventeen antibiotics were selected in  antibiotics sensitivity test. Imipenem 10mg was the best antimicrobial effect. The results showed that all three concentrations had  good antibacterial effect. It has also been shown that methanol solvent is more effective on bacteria than n-hexane solvent. Also, the  results showed that P. aeroginosa and S. auereu has the highest rate of inhibition diameter with methanol solvent (38.123 ± 0.07 and  35.133 ± 0.092) mm respectively. While K. pnemeumonia was the highest rate of inhibition diameter by n- hexane solvent  32.4 ± 0.07 mm. Methanol and n-hexane extracts of Quercus rubra can be regarded as a potential antibacterial against aerobic pathogenic  bacteria isolated from patients with burn infection. Therefore, Fruit casings of Quercus rubra may be considered as a raw material for the manufacture of ointment for treatment of burns infections. 

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Authors

Dhafer Rahman Abed Al-janabi
dhafer221@gmail.com (Primary Contact)
Enas Abd al-Raouf Ammar Semysim
Dhafer Rahman Abed Al-janabi, & Enas Abd al-Raouf Ammar Semysim. (2020). Antibacterial activity of Methanol and n-Hexane extracts of fruit casings of Quercus rubra against multi-drug resistance pathogenic bacteria isolated from patients with burn infection. International Journal of Research in Pharmaceutical Sciences, 11(3), 4303–4310. Retrieved from https://ijrps.com/home/article/view/1060

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