Abstract
Many studies have been conducted for the role of Ahara (~dietary habits), Vihara (~abnormal Physical activity) and Manas (~Psychological factors) and their association with pathogenesis of Ulcerative colitis, which is a subtype of inflammatory bowel disease, which pursue a protracted relapsing and remitting course, usually extending over years. The causes of relapsing of ulcerative colitis are not known. Dietary factors have been associated in the pathogenesis of ulcerative colitis as well as associated with an increased risk of relapse of ulcerative colitis. Here, we have reviewed the probable mechanisms of the role of diet and its association with pathogenesis of Ulcerative colitis (UC). In Ayurveda, on the basis of signs and symptoms ulcerative colitis can be best compared with Raktatisara. This article is an attempt to do critical review and put a light on the role of diet, faulty lifestyle and Psychological factors in occurrence and progression of Ulcerative colitis (UC), and try to explain Etiopathogenesis of Raktatisara in relation to ulcerative colitis by going through Ayurvedic texts, Google Scholar, PubMed journals etc.
Full text article
References
Brown, K., et al. 2012. Diet-Induced Dysbiosis of the Intestinal Microbiota and the Effects on Immunity and Disease. Nutrients, 4(8):1095–1119.
Geerling, B. J., et al. 2000. Diet as a risk factor for the development of ulcerative colitis. The American Journal of Gastroenterology, 95(4):1008–1013.
Govindaraj, P., et al. 2015. Genome-wide analysis correlates Ayurveda Prakriti. Scientific Reports, 5(1):15786.
Jowett, S. L. 2004. Influence of dietary factors on the clinical course of ulcerative colitis: a prospective cohort study. Gut, 53(10):1479–1484.
Keefer, L., et al. 2008. Reconsidering the methodology of stress research in inflammatory bowel disease. Journal of Crohn’s and Colitis, 2(3):193–201.
Langholz, E., et al. 1994. Course of ulcerative colitis: Analysis of changes in disease activity over years. Gastroenterology, 107(1):3–11.
Lennard-Jones, J. E., et al. 1965. Prednisone As Maintenance Treatment for Ulcerative Colitis in Remission. The Lancet, 285(7378):188–189.
Nicolas, A. 2006. Davidson’s Principles & Practice of Medicine. page 1381. Churchill Livingstone.
Nicolas, A., et al. 2006a. ‘Davidson’s Principles & Practice of Medicine’. page 912. Churchill Livingstone.
Nicolas, A., et al. 2006b. ‘Davidson’s Principles & Practice of Medicine’. page 913. Churchill Livingstone.
Persson, P.-G., et al. 1992. Diet and Inflammatory Bowel Disease: A Case-Control Study. Epidemiology, 3(1):47–52.
Ramos, G. P., Papadakis, K. A. 2019. Mechanisms of Disease: Inflammatory Bowel Diseases. Mayo Clinic Proceedings, 94(1):155–165.
Rutgeerts, P., Geboes, K. 2001. Understanding inflammatory bowel disease-the clinician’s perspective. European Journal of Surgery, 167(S8):66–72.
Sartor, R. B. 2006. Mechanisms of Disease: pathogenesis of Crohn’s disease and ulcerative colitis. Nature Clinical Practice Gastroenterology & Hepatology, 3(7):390–407.
Satsangi, J., et al. 1997. The genetics of inflammatory bowel disease. Gut, 40(5):572–574.
Sharma, A. 2008. Sushruta Samhita, Uttartantra. Pages 293, 40/10. Varanasi, India. Chaukhamba Surbharati Prakashan.
Shukla, V., Tripathi, R. D. 2002a. ‘Charaka Samhita’. Chikitsasthana. Pages- 477, 19/70, Varanasi, India. Chaukhambha Sanskrit Sansthan.
Shukla, V., Tripathi, R. D. 2002b. ‘Charaka Samhita’. Chikitsasthana. Pages- 466, 19/6, Varanasi, India. Chaukhambha Sanskrit Sansthan.
Shukla, V., Tripathi, R. D. 2002c. ‘Charaka Samhita’. Chikitsasthana. Pages- 466, 19/69, Varanasi, India. Chaukhambha Sanskrit Sansthan.
Sood, A. 2003. Incidence and prevalence of ulcerative colitis in Punjab, North India. Gut, 52(11):1587–1590.
Thompson, A. I., Lees, C. W. 2011. Genetics of ulcerative colitis. Inflammatory Bowel Diseases, 17(3):831–848.
Ungaro, R., et al. 2017. Ulcerative colitis. The Lancet, 389(10080):1756–1770.
Authors
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.