C-reactive protein and other markers of inflammation in the prediction of car- diovascular disease in diabetes

Abstract

The metabolic syndrome is a clustering of risk factors of metabolic origin that increase the risk components of metabolic starting point that expansion the risk for cardiovascular disorders and type 2 diabetes. Our aim is to evaluate the inflammation in Diabetes patients. The study was conducted at SLIMS, Puducherry. The study included 200 diabetic patients and 200 Controls. All results were summarized as mean ± SEM. The components by which chronic inflammation can bring out type II diabetes are not clear. Inflammatory markers such as CRP, hsCRP, Oxi LDL increased in DM when compared with controls (p<0.01). Pro-inflammatory cytokines and intense stage reactants are engaged with different metabolic pathways significant to insulin protection, including insulin regulation, receptive oxygen species, lipoprotein lipase activity and adipocyte function. Along these lines, actuated natural insusceptibility and inflammation are applicable factors in the pathogenesis of diabetes, with persuading information that type II diabetes incorporates an inflammatory component.