Evaluation of thyroid profile and oxidative stress and antioxidants parameters in chronic sinusitis

Abstract

Oxidative stress, which is characterized as a misbalance between free radicals and antioxidants in favour of radicals, participates in the pathogenesis of many diseases and their complications. A free radical is a molecule or molecular fragment that contains one or more unpaired electrons in its outer orbit. The study consisted to a total of 80 subjects; 40 patients and 40 controls. 5 ml of random blood sample was collected from each of the cases and controls were studied parameters Thyroid profile (T3, T4, TSH), Vitamin C. Chronic sinusitis is associated with oxidative stress. Thyroid profile in chronic sinusitis patients is normal. Our findings demonstrate that detection of thyroid hormone status in addition to other biochemical variables in the early stage of the disease will help the patient to improve and reduce the morbidity rate.