Evaluation of anti-inflammatory activity of Jasminum sessiliflorum extracts

Abstract

Medicinal plants are important resources for the development of novel anti-inflammatory agents. Synthetic anti-inflammatory drugs have several adverse effects. Medicinal plants have numerous bioactive phytoconstituents that are safer as well as better substitutes for the prevention and management of various diseases and disorders. The ethanolic and ethyl acetate extracts of Jasminum sessiliflorum were evaluated for their potential as anti-inflammatory agents in vivo by inducing paw edema in rats using carrageenan. The anti-inflammatory activity of the reference drug was compared with the extracts of Jasminum sessiliflorum. The extracts on screening indicated the presence of phyto-constituents such as phenolics, terpenoids, flavonoids, alkaloids, and saponins. The study established significant anti-inflammatory nature of the Jasminum sessiliflorum extracts in a manner which is dose-dependent. The results indicate that both the extracts of Jasminum sessiliflorum possess anti-inflammatory activity of significance and can be used in the development for novel anti-inflammatory moieties.