Interleukin-6 gene polymorphism (-174 G/C) association with seropositive Toxoplasma gondii infection patients in Al-Diwaniyah hospital

Abstract

The present study aims to detection Interleukin-6 gene polymorphism (-174 G/C) from seropositive Toxoplasma gondii pregnant women patients and healthy control from individuals reviewers to AL-Diwaniyah hospital. 80 samples were collected for the period from October 2018- April 2019, including two groups of 30 samples healthy control and 50 samples from pregnant women infected with Toxoplasma gondii.  The results of the present study indicated the presence of IL-6 (-174 G/C) polymorphism in pregnant women infected with Toxoplasma gondii and healthy control. Where was observed that CG genotype more frequent in patients indicating the association of this genotype with the disease compared to the control group where CG genotype appears less. Also, the results of the current study indicate the appearance of allele C more frequently in pregnant women patients compared to healthy control. We can conclude from the present study there association of appearance allele C with Toxoplasma gondii infection.