Evaluation of antimicrobial property of few co-polyesters

Tamilarasan K (1) , Nanthini R (2) , Prakash N (3) , Rajkumar E (4) , Renganathan N.G (5) , Udaya Prakash N.K (6)
(1) Research Scholar, Department of Chemistry, Pachaiyappa’s College, University of Madras, Chennai-600030, Tamil Nadu, India, India ,
(2) Department of Chemistry, Pachaiyappa’s College, University of Madras, Chennai-600030, Tamil Nadu, India, India ,
(3) Department of Chemistry, Vel Tech Dr. RR Dr. SR Technical University, Avadi, Chennai-600062, Tamil Nadu, India, India ,
(4) Department of Chemistry, Vel Tech Dr. RR Dr. SR Technical University, Avadi, Chennai-600062, Tamil Nadu, India, India ,
(5) Department of Chemistry, Vel Tech Dr. RR Dr. SR Technical University, Avadi, Chennai-600062, Tamil Nadu, India, India ,
(6) Department of Chemistry, Vel Tech Dr. RR Dr. SR Technical University, Avadi, Chennai-600062, Tamil Nadu, India, India

Abstract

Aliphatic random co-polyesters Poly (Propane1,3-diol Fumaric acid 1,4-cyclohexanedimethanol) (PPFCDM), Poly (Propane1, 3-diol Fumaric acid Pimelic acid (PPFPi), Poly (Butane1,4-diol Fumaricacid 1, 4-cyclohexanedimethanol (PBFCDM), Poly (1,4-Cyclohexanedimethanol Pimelicacid 1,4-Cyclohexanedicarboxylic acid) (PCDMPiCDC) Poly (1,4-Cyclohexanedimethanol Fumaricacid 1,4-Cyclohexanedicarboxylicacid (PCDMFCDC) were synthesized from propane1, 3-diol and 1, 4-cyclohexane dimethanol with various carboxylic acids in the presence of catalyst using microwave technique. The antimicrobial efficacy was evaluated using well diffusion method against gram positive bacteria (Bacillus cereus), gram negative bacteria (Escherichia coli) and yeast (Candida albicans). Streptomycin and Ketoconazole were used as a positive control against the studied bacteria and yeast respectively. These results show that random copolyesters possess mild activities against microorganisms selected.

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Authors

Tamilarasan K
Nanthini R
Prakash N
srideviprakash1987@gmail.com (Primary Contact)
Rajkumar E
Renganathan N.G
Udaya Prakash N.K
Tamilarasan K, Nanthini R, Prakash N, Rajkumar E, Renganathan N.G, & Udaya Prakash N.K. (2013). Evaluation of antimicrobial property of few co-polyesters. International Journal of Research in Pharmaceutical Sciences, 4(4), 604–607. Retrieved from https://ijrps.com/home/article/view/3754

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