In vitro anthelmintic activity of Annona Reticulata leaves extract against Eisinia fetida

Abstract

Crude extracts of leaves of Annona Reticulata (Annonaceae) were evaluated for in vitro anthelmintic activity on the Indian adult earthworms Eisinia fetida. The leaves extracts of Annona Reticulata had shown a dose dependant inhibition of spontaneous motility (Paralysis) of earthworms. It has been observed that methanolic extract (100 mg/ml) has shown anthelmintic activity, which was compared with Albendazole as reference drug. Therefore the leaves could be categorized under anthelmintic herbal drugs and could become a potent key ingredient of such herbal formulation.