Anti inflammatory potential of alcoholic extract of resvaretrol from fruits of Vitis vinifera linn.

Abstract

Anti-inflammatory activity of the ethanolic extracts of the fruits of resvaretrol in Vitis vinifera linn was studied in Sprague dowley rats using the carrageenan induced left hind paw edema. The ethanolic extracts at the dose of 500 mg/kg body weight shows moderate to significant anti-inflammatory activity. The ethanolic extracts of resvaretrol in Vitis vinifera linn reduced the edema induced by carrageenan by 25.87 % on oral administration of 500 mg/kg body weight as compared to the untreated control group. Diclofenac sodium at 10 mg/kg body weight inhibited the edema volume by 37.79%. The results indicated that the ethanolic extract 500 mg/kg body weight shows more significant (p<0.05) anti-inflammatory activity when compared with the standard and untreated control.