Cyclization of microbiologically active 4-(furan-2-yl)-1-(pyridine-4-yl)-azetidine-2-one derivatives

Sandip Sen (1) , Biplab De (2) , Easwari T.S. (3) , Nagarajan A.S. (4) , Sandeep Maurya (5)
(1) IIMT College of Medical Sciences, O.Pocket, Ganganagar, Meerut, Uttar Pradesh, India, India ,
(2) Regional Institute of Pharmaceutical Science and Technology, Abhoynagar, Agartala, Tripura, India, India ,
(3) IIMT College of Medical Sciences, O.Pocket, Ganganagar, Meerut, Uttar Pradesh, India, India ,
(4) Central Leather Research Institute, Industrial Chemistry Laboratory, Adyar, Chennai, Tamil Nadu, India, India ,
(5) IIMT College of Medical Sciences, O.Pocket, Ganganagar, Meerut, Uttar Pradesh, India, India

Article Sidebar

Issue
Vol. 2 No. 2 (2011): Volume 2 Issue 2
Keywords:
    Furfuraldehyde, Imines, Column chroatography, Azetidines, Antimicrobial
PDF

Abstract

The present work involved cyclization of imines by reaction with chloro-methtlene chloride using 1, 4-dioxane as solvent (2a&2b). The imines were formed by reaction with furan-2-carboxyldehyde and various substituted heterocyclic amines (1a&1b). The cyclic derivatives were found to be associated with diverse antimicrobial activity.

Full text article

Generated from XML file

Authors

Sandip Sen
IIMT College of Medical Sciences, O.Pocket, Ganganagar, Meerut, Uttar Pradesh, India
sandipsen2010@gmail.com (Primary Contact)
Biplab De
Regional Institute of Pharmaceutical Science and Technology, Abhoynagar, Agartala, Tripura, India
Easwari T.S.
IIMT College of Medical Sciences, O.Pocket, Ganganagar, Meerut, Uttar Pradesh, India
Nagarajan A.S.
Central Leather Research Institute, Industrial Chemistry Laboratory, Adyar, Chennai, Tamil Nadu, India
Sandeep Maurya
IIMT College of Medical Sciences, O.Pocket, Ganganagar, Meerut, Uttar Pradesh, India
Sandip Sen, Biplab De, Easwari T.S., Nagarajan A.S., & Sandeep Maurya. (2011). Cyclization of microbiologically active 4-(furan-2-yl)-1-(pyridine-4-yl)-azetidine-2-one derivatives. International Journal of Research in Pharmaceutical Sciences, 2(2), 183–186. Retrieved from https://ijrps.com/home/article/view/3112
Download Citation
Endnote/Zotero/Mendeley (RIS) BibTeX

Article Details

No Related Submission Found