Synthesis, Characterization And Assessment of Anti Microbial Behaviour of Goat Faecal Mediated Silver Nanoparticles - Fed on Tirumala Hills

Shakir Basha S (1) , Ashok Thulluru (2) , Naresh Babu C (3) , Chithra Shekar C (4) , Jagadeesh P (5) , Mohammed Idress N S (6) , Praveena R (7) , Sravan Kumar C (8) , Anil A (9)
(1) Department of Pharmaceutical Analysis, Raghavendra Institute of Pharmaceutical Education and Research (Autonomous), K. R.Palli Cross, Chiyyedu (Post) – 515721, Anantapuramu (Dist), Andhra Pradesh, India, India ,
(2) Department of Pharmaceutics, Shri Vishnu College of Pharmacy (Autonomous), Vishnupur, Bhimavaram-534202, W.G. (Dist), Andhra Pradesh, India, India ,
(3) Department of Pharmaceutical Chemistry, Raghavendra Institute of Pharmaceutical Education and Research (Autonomous), K. R.Palli Cross, Chiyyedu (Post) – 515721,Anantapuramu (Dist), Andhra Pradesh, India, India ,
(4) Department of Pharmacy, Sree Vidyanikethan College of Pharmacy, SreeSainath Nagar, A. Rangampet, Tirupathi – 517102, Andhra Pradesh, India, India ,
(5) Department of Pharmaceutical Analysis, Raghavendra Institute of Pharmaceutical Education and Research (Autonomous), K. R.Palli Cross, Chiyyedu (Post) – 515721, Anantapuramu (Dist), Andhra Pradesh, India, India ,
(6) Department of Pharmacy, Sree Vidyanikethan College of Pharmacy, SreeSainath Nagar, A. Rangampet, Tirupathi – 517102, Andhra Pradesh, India, India ,
(7) Department of Pharmacy, Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, A. Rangampet, Tirupathi – 517102, Andhra Pradesh, India, India ,
(8) Department of Pharmacy, Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, A. Rangampet, Tirupathi – 517102, Andhra Pradesh, India, India ,
(9) Department of Pharmacy, Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, A. Rangampet, Tirupathi – 517102, Andhra Pradesh, India, India

Abstract

To synthesize, characterize, and to assess the anti-microbial activity of silver nanoparticles (AgNPs) induced by goat fecal matter. The AgNPs were processed by the microwave heating method and the characterization was accomplished by employing various spectroscopic approaches such as UV-Visible, FTIR spectroscopy, XRD, Particle size, and Zeta potential analysis. The lmax for both extracts were found at 426& 438nm. The wideband corresponded to O-H stretching vibrations at 3384.0 cm-1, 3273.9 cm-1 and 3366.2 cm-1, bands at 2918.5 cm-1, 2922.5 cm-1, 2853.2 cm-1, and 2850.2 cm-1 corresponded to the N–H and C–H stretching. The bands at 1638.1 cm-1, 1651.9, and 1686.5 cm-1 corresponded to the C=C stretch. Bands of 1460.3 cm-1, 1450.4 cm-1, 1409.2 cm-1 and 1376.3 cm-1 corresponded to C-N, C-C bond stretching vibrations. The stretch of C-O indicates bands at 1159.7 cm-1, 1033.2 cm-1, and 1032.8 cm-1. The synthesized AgNPsdemonstrated good anti-microbial activity on gram +Ve (S.aureus) and gram -Ve (E.coli) bacteria. Bio/Green synthesized AgNPs have shown improved biological performance, this tends to minimize production cost, pollution-free, less chemical usage, and stable generation of nanoparticles.

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Authors

Shakir Basha S
shakirbasha72@gmail.com (Primary Contact)
Ashok Thulluru
Naresh Babu C
Chithra Shekar C
Jagadeesh P
Mohammed Idress N S
Praveena R
Sravan Kumar C
Anil A
Shakir Basha S, Ashok Thulluru, Naresh Babu C, Chithra Shekar C, Jagadeesh P, Mohammed Idress N S, Praveena R, Sravan Kumar C, & Anil A. (2021). Synthesis, Characterization And Assessment of Anti Microbial Behaviour of Goat Faecal Mediated Silver Nanoparticles - Fed on Tirumala Hills. International Journal of Research in Pharmaceutical Sciences, 12(2), 1223–1232. Retrieved from https://ijrps.com/home/article/view/149

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