To study the effect of oral vitamin D supplements on wound healing in patient with diabetic foot ulcer and its effect on lipid metabolism

Ajoinish Kamble (1) , Ranjit S. Ambad (2) , Mangesh Padamwar (3) , Anupam Kakade (4) , Meenakshi Yeola (5)
(1) Department of Surgery, Datta Meghe Medical College, Shalinitai Meghe Hospital & Research Centre, Hingana, Nagpur, Maharashtra, India, India ,
(2) Department of Biochemistry, Datta Meghe Medical College, Shalinitai Meghe Hospital & Research Centre, Hingana, Nagpur, Maharashtra, India, India ,
(3) Department of General Surgery, Datta Meghe Medical College, Shalinitai Meghe Hospital and Research Centre (Datta Meghe Institute of Medical Sciences), Hingana, Nagpur-441110, India, India ,
(4) Department of General Surgery, Datta Meghe Medical College, Shalinitai Meghe Hospital and Research Centre (Datta Meghe Institute of Medical Sciences), Hingana, Nagpur-441110, India, India ,
(5) Department of General Surgery, Jawaharlal Nehru Medical College, (Datta Meghe Institute of Medical Sciences), Sawangi Meghe Wardha, India, India

Abstract

To Critically Assess the effect of oral vitamin D supplements on wound healing in patient with diabetic foot ulcer and its effect on lipid metabolism.This is a single-Centre prospective randomized, control-controlled study was conducted in Department of Surgery Datta Meghe Medical College, Hingna, Nagpur, in collaboration with Datta Meghe Institute of Medical Sciences (DMIMS) Deemed to be University from June 2019 TO March 2020. Total 60 patients were included in this study randomized grouping were done, group A vitamin d supplements and group B as control group.In group A vitamin D levels were significantly increased after 12 weeks of intervention as compared to baseline while in group B no change was seen after intervention. After 12 week of intervention, comparison of group A vs. group B, we found that Vitamin D HbA1c, TC, HDL and Wound surface area, significantly improved while there was no change seen in triglycerides levels in both the group.After intervention with vitamin D supplements for 12 weeks among patients with diabetic foot ulcer had good result and beneficial effect on glucose metabolism, vitamin D levels, lipid profile and wound healing.

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Authors

Ajoinish Kamble
Ranjit S. Ambad
Ambad.sawan@gmail.com (Primary Contact)
Mangesh Padamwar
Anupam Kakade
Meenakshi Yeola
Ajoinish Kamble, Ranjit S. Ambad, Mangesh Padamwar, Anupam Kakade, & Meenakshi Yeola. (2020). To study the effect of oral vitamin D supplements on wound healing in patient with diabetic foot ulcer and its effect on lipid metabolism. International Journal of Research in Pharmaceutical Sciences, 11(2), 2701–2706. Retrieved from https://ijrps.com/home/article/view/1321

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